Management of acute asthma exacerbation in adults

BTS algorithm
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Notes in Asthma

CXR is recommended only in the following settings: –

  • Suspected pneumothorax, pneumomediastinum, pneumonia
  • Life threatening features
  • Failure to respond to standard treatment
  • Patients requiring ventilation

Transfer to ICU accompanied by a doctor prepared to intubate if:

  1. Deteriorating PEF, worsening or persisting hypoxia, or hypercapnia
  2. Exhaustion, altered consciousness
  3. Poor respiratory effort or respiratory arrest

NIV should only be considered as a treatment for life threatening asthma when a senior intensivist/ anaesthetist that can proceed directly to intubation is present with the patient in the ED.

In management of pregnant patients — obstetrician input is recommended in cases of severe asthma and continuous foetal monitoring commenced.

Regardless of the PEFR, when any of the following features are present, admission may be appropriate:

  • Life-threatening features at any time
  • Pregnancy
  • Lives alone
  • Still have significant symptoms
  • Concern over compliance
  • Psychosocial problems
  • Physical disability or learning difficulties
  • History of severe asthma
  • Presentation at night
  • Exacerbation despite adequate dose steroids pre-presentation

Patients considered for discharge should meet all of the following criteria:

  • No life-threatening features at any point (including pre-hospital)
  • No features of severe asthma after initial treatment
  • PEFR >75% best or predicted and stable one hour after initial treatment

OR

  • PEFR > 50% best or predicted and stable two hours after initial treatment